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Metformin

Diabetes

Also known as Glucophage, Fortamet

Metformin is usually the first medicine people take for type 2 diabetes. It tells your liver to release less sugar and helps your muscles respond better to insulin. It doesn't cause weight gain and rarely causes low blood sugar on its own, which is why doctors like it as a starting point.

How to take it

When

Usually once or twice a day, exactly as prescribed.

Food

Take it with a meal. Food dramatically reduces the stomach upset it's known for.

Avoid

Heavy or binge drinking — combined with metformin it can stress your body in a dangerous way.

When sick

If you're vomiting, have diarrhea, or can't keep fluids down, call your doctor. They may pause the medicine until you recover.

Missed a dose?

Take it with your next meal and carry on as normal. Don't take a double dose to make up for it.

Common side effects

  • Nausea, diarrhea, or a metallic taste — very common in the first weeks and usually settles
  • Mild stomach cramps
  • Long-term use can lower vitamin B12 — your doctor may check this occasionally

Call a doctor if

Educational only. This summary is drawn from public FDA labeling and MedlinePlus and simplified for readability. Your prescription label and your pharmacist always come first — doses and instructions vary from person to person.