Fexofenadine
AllergyAlso known as Allegra
Fexofenadine is a non-drowsy antihistamine — it blocks histamine, the chemical behind sneezing, itching, and runny nose. It's the least sedating of the common allergy pills, which makes it a good pick if other antihistamines make you foggy. The one thing to know: fruit juice genuinely interferes with how your body absorbs it, so what you swallow it with actually matters.
How to take it
When
Take it as the label or your doctor directs — some versions are once a day, others twice.
Food
Take it with plain water only. Orange, apple, and grapefruit juice cut down how much your body absorbs, so skip juice within a few hours of your dose.
Avoid
Don't take it at the same time as antacids that contain aluminum or magnesium — space them apart by a couple of hours.
Good to know
It's the least likely of the big three allergy pills to make you drowsy, so it's a favorite for people who drive or operate machinery.
Missed a dose?
If you take it on a schedule and miss a dose, take it when you remember. If it's close to your next dose, skip the missed one. Never double up.
Common side effects
- Headache
- Nausea
- Dizziness (uncommon)
- Cold-like symptoms such as cough or back discomfort
Call a doctor if
- Trouble breathing, or swelling of your face, lips, or tongue — call emergency services now. An allergy pill is not a substitute for epinephrine in a severe reaction.
- Hives with throat tightness or feeling faint — get emergency help
- A rash that spreads or blisters
- Symptoms that keep getting worse despite taking it — see a doctor