Esomeprazole
Stomach and refluxAlso known as Nexium
Esomeprazole is a proton pump inhibitor — the same family as omeprazole. It shuts off many of the tiny pumps in your stomach that make acid, giving reflux, ulcers, and an irritated food pipe a chance to heal. It's a preventer, not a rescue: it works best taken daily before a meal, not popped when heartburn is already raging.
How to take it
When
Take it 30 to 60 minutes before a meal, usually breakfast — it needs those acid pumps active to do its job.
Food
Take it before food, not after. If swallowing capsules is hard, ask your pharmacist — some can be opened and sprinkled on applesauce, but never crushed or chewed.
Don't crush
The granules inside have a protective coating. Crushing or chewing them destroys it and the medicine won't work properly.
Good to know
Long-term daily use should be a decision you make with your doctor, not a habit that just continues — check in about whether you still need it.
Missed a dose?
If you miss a dose, take it as soon as you remember that day. If it's close to your next dose, skip the missed one. Never take two doses at once.
Common side effects
- Headache
- Diarrhea or constipation
- Nausea
- Gas or stomach pain
- Dry mouth
Call a doctor if
- Black, tarry stools or vomit that looks like coffee grounds — this can mean bleeding in your stomach. Get help now.
- Trouble swallowing, or food feeling stuck — call your doctor right away.
- Watery diarrhea that won't stop, especially with fever — call your doctor.
- New or worsening joint pain with a rash on your cheeks or arms that gets worse in the sun — call your doctor.