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Alendronate

Bones, joints, and gout

Also known as Fosamax

Alendronate treats osteoporosis by slowing the cells that break down bone, so your bones can rebuild density and resist fractures. It works quietly over months and years. The one thing you must get right is how you take it: the pill can badly burn your food pipe if it doesn't go straight down and stay down, so the morning ritual isn't a suggestion — it's the whole deal.

How to take it

When

First thing in the morning, empty stomach, with a full glass of plain water — nothing else.

Food

No food, drink, or other pills for at least 30 minutes after. Plain water only.

Avoid

Lying down for at least 30 minutes after taking it — stay sitting or standing upright.

Good to know

Take calcium and vitamin D at a DIFFERENT time of day — they block this medicine.

Missed a dose?

For the once-weekly version, take it the next morning after you remember, then go back to your regular day. Never take two tablets on the same day, and never double up.

Common side effects

  • Heartburn or stomach upset
  • Nausea
  • Constipation or diarrhea
  • Bone, joint, or muscle aches
  • Bloating

Call a doctor if

Educational only. This summary is drawn from public FDA labeling and MedlinePlus and simplified for readability. Your prescription label and your pharmacist always come first — doses and instructions vary from person to person.