Acetaminophen
Pain and inflammationAlso known as Tylenol
Acetaminophen relieves pain and lowers fever, and unlike ibuprofen or naproxen, it doesn't irritate the stomach — which is why it's often the go-to when NSAIDs aren't a good fit. The one thing you really need to know: it's processed by your liver, and too much can cause serious liver damage. It also hides inside many cold, flu, and combination pain products, so check every label and count all your acetaminophen together.
How to take it
When
As needed for pain or fever. Space doses as the label directs and never exceed the daily maximum on the label.
Food
With or without food — it's easy on the stomach either way.
Avoid
Don't stack it with cold, flu, or sleep products that also contain acetaminophen. If you have three or more alcoholic drinks a day, talk to your doctor before using it.
Good to know
An overdose can be silent at first — you might feel fine for a day or more while damage is happening. If you think you took too much, get help right away, even if you feel okay.
Missed a dose?
Acetaminophen is usually taken as needed, so there's no missed dose to worry about. If you take it on a schedule, take it when you remember unless the next dose is close. Never double up.
Common side effects
- Side effects are uncommon at normal doses
- Nausea
- Headache
- Mild rash
Call a doctor if
- You took more than the label's daily maximum, or you're not sure — call Poison Control or get help now, even if you feel completely fine. Early treatment protects your liver.
- Yellowing of your skin or eyes, dark urine, or pain in the upper right belly — signs of liver trouble. Get medical help right away.
- A rash with blistering or peeling skin — stop taking it and get help now.
- Swelling of the face, lips, or throat, or trouble breathing — call emergency services.